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What is an AST Test? AST (aspartate aminotransferase) is an enzyme that is found mostly in the liver, but it's also in muscles and other organs in your body. When cells that contain AST are damaged, they release the AST into your blood. An AST blood test measures the amount of AST in your blood. The test is commonly used to help diagnose liver damage or disease. Other names: SGOT test, serum glutamic oxaloacetic transaminase test; aspartate transaminase test What is it used for? An AST blood test is often part of a routine blood screening to check the health of your liver. The test may help diagnose or monitor liver problems. It may also help diagnose other health conditions. Why do I need an AST blood test? You may get an AST blood test as part of your routine checkup or if you have symptoms of liver damage. These may include: Nausea and vomiting Lack of appetite Fatigue Weakness Jaundice, is a condition that causes your skin and eyes to turn yellow Swelling and/or pain in your ab