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What is homocysteine? How is a high homocysteine level harmful? High homocysteine levels in the blood can damage the lining of the arteries. High levels may also make the blood clot more easily than it should. This can increase the risk of blood vessel blockages. A clot inside your blood vessel is called a thrombus. A thrombus can travel in the bloodstream. From there, it can get stuck in your: Lungs (called a pulmonary embolism) Brain (which can cause a stroke) Heart (which can cause a heart attack) Some people have very high levels of homocysteine. They are at an increased risk for heart disease. What causes a high homocysteine level? Homocysteine is normally changed into other amino acids for use by the body. Vitamin B helps your body use the homocysteine. If your homocysteine level is too high, you may not be getting enough B vitamins. Most people who have a high homocysteine level don’t get enough folate (also called folic acid), vitamin B6, or vitamin B12 in their diet. Replacing...